MINFLUX in two colors and three dimensions with localization accuracies better than 1 nm.
Please check out the new publication:
Gwosch, K.C., Pape, J.K., Balzarotti, F. et al. "MINFLUX nanoscopy delivers 3D multicolor nanometer resolution in cells". Nat Methods (2020)
MINFLUX (minimal photon flux) is the cutting-edge method for localizing fluorescent molecules with unprecedented precision.
By introducing the MINFLUX nanoscope, Abberior Instruments offers the first commercially available light microscope with a resolution of the size of a molecule.
Learn how to stay sharp, even when focusing deep into tissue here.
Using Abberior STED-FCS, a team from four European countries, comprising Christian Eggeling (Leibniz IPHT & Friedrich Schiller University Jena) and Delphine Muriaux (Montpellier Infectious Disease Research Institute) discovered the existence and composition of a lipid-based platform for HIV virus assembly.
These results provide novel molecular insights on HIV virus assembly and are a starting point for the development of new antiviral drugs.
Citation: C. Favard, J. Chojnack, P. Merida, N. Yandrapalli, J. Mak, C. Eggeling and D. Muriaux, "HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly", Science Advances, 02 Oct 2019: Vol. 5, no. 10.
Our new push-button STEADYFOCUS module ensures that your images are perfectly in focus over days.
Please check out the new Publication (link below):
A combination of expansion microscopy and DyMIN 3D STED reveals the ultrastructure of centrioles. Chlamydomonas reinhardtii centrioles immunostained with Abberior STAR RED for polyglutamylated tubulin. Samples by P. Guichard & D. Gambarotto (University of Geneva).
D. Gambarotto, F. U. Zwettler, M. Le Guennec, M. Schmidt-Cernohorska, D. Fortun, S. Borgers, J. Heine, J. G. Schloetel, M. Reuss, M. Unser, E. S. Boyden, M. Sauer, V. Hamel & P. Guichard, “Imaging cellular ultrastructures using expansion microscopy (U-ExM)”, Nature Methods (2019)
DyMIN STED is a co-development between Stefan Hell and coworkers and Abberior Instruments. Read all technical details in the current PNAS publication, 2017:
J. Heine, M. Reuss, B. Harke, E. D'Este, S. J. Sahl and S. W. Hell, "Adaptive-illumination STED nanoscopy", PNAS (2017)
Nature review on DyMIN STED: G. Pacchioni, "Always look on the bright side of the fluorophore", Nature Review Materials (2017)
Follow along with the incredibly quick installation of a STEDYCON super resolution microscope, uncut. We go from opening the carton to the first super-resolution STED image in under three minutes. Don't forget to check out the real time movie here: https://youtu.be/wnFnyt8yJyA