IMAGING BEYOND BARRIERS!
MINFLUX goes 3D
Below 3 x 3 x 3 nm resolution in all directions
Please check out the new publication:
K. C. Gwosch, J. K. Pape, F. Balzarotti, P. Hoess, J. Ellenberg, J. Ries, S. W. Hell "MINFLUX nanoscopy delivers multicolor nanometer 3D-resolution in (living) cells", bioRxiv (2019)
NEW: Abberior Instruments STEADYFOCUS
Boost your stability:
Our new push-button STEADYFOCUS module ensures that your images are perfectly in focus over days.
NEW: Abberior Instruments Facility Line
Guided STED nanoscopy enables super-resolution imaging of blood stage malaria parasites
Please check out the new Publication:
J.-G. Schloetel, J. Heine, A. F. Cowman, M. Pasternak, "Guided STED nanoscopy enables super-resolution imaging of blood stage malaria parasites", Nature Scientific Reports, Volume 9, Article number: 4674 (2019)
Collaboration SVI and Abberior Instruments
The recent and most fruitful collaboration between Abberior Instruments and SVI has brought about cutting-edge superresolution at maximum convenience and benefit for our STEDYCON users.
As exemplified in the panels below, the combination of top-notch STED imaging with a sophisticated deconvolution method reveals the faintest details in the sample. Moreover, all this unfolds at the push of a button!
For any questions & quotations: sales@abberior-instruments.com
Impressions
DyMIN STED + easy3D STED = unprecedented 3D STED resolution
Please check out the new Publication (link below):
A combination of expansion microscopy and DyMIN 3D STED reveals the ultrastructure of centrioles. Chlamydomonas reinhardtii centrioles immunostained with Abberior STAR RED for polyglutamylated tubulin. Samples by P. Guichard & D. Gambarotto (University of Geneva).
D. Gambarotto, F. U. Zwettler, M. Le Guennec, M. Schmidt-Cernohorska, D. Fortun, S. Borgers, J. Heine, J. G. Schloetel, M. Reuss, M. Unser, E. S. Boyden, M. Sauer, V. Hamel & P. Guichard, “Imaging cellular ultrastructures using expansion microscopy (U-ExM)”, Nature Methods (2019)
Correlative microscopy approach for biology using X-ray holography and STED microscopy
Please check out the new Publication:
M. Bernhardt, J.-D. Nicolas, M. Osterhoff, H. Mittelstädt, M. Reuss, B. Harke, A. Wittmeier, M. Sprung, S. Köster, T. Salditt, "Correlative microscopy approach for biology using X-ray holography, X-ray scanning diffraction and STED microscopy", Nature Communications, Volume 9, Article number: 3641 (2018)
Three dimensional live-cell STED microscopy at increased depth using a water immersion objective
Our patent protected easy3D STED technology produces superior 3D STED data – please check out our new publication:
J. Heine, C. A. Wurm, J. Keller-Findeisen, A. Schönle, B. Harke, M. Reuss, F. R. Winter, G. Donnert, "Three dimensional live-cell STED microscopy at increased depth using a water immersion objective", Review of Scientific Instruments (2018)
Explanation videos of Adaptive Illumination (DyMIN, RESCue and MINFIELD STED)
DyMIN STED is a co-development between Stefan Hell and coworkers and Abberior Instruments. Read all technical details in the current PNAS publication, 2017:
J. Heine, M. Reuss, B. Harke, E. D'Este, S. J. Sahl and S. W. Hell, "Adaptive-illumination STED nanoscopy", PNAS (2017)
Nature review on DyMIN STED: G. Pacchioni, "Always look on the bright side of the fluorophore", Nature Review Materials (2017)
From zero to STED in no time
Follow along with the incredibly quick installation of a STEDYCON super resolution microscope, uncut. We go from opening the carton to the first super-resolution STED image in under three minutes. Don't forget to check out the real time movie here: https://youtu.be/wnFnyt8yJyA