Publications

A. N. Butkevich , V. N. Belov, K. Kolmakov, V. V. Sokolov, H. Shojaei, S. C. Sidenstein, D. Kamin, J. Matthias, R. Vlijm, J. Engelhardt, S. W. Hell, "Hydroxylated Fluorescent Dyes for Live-Cell Labeling: Synthesis, Spectra and Super-Resolution STED Microscopy", Chem. Eur. J., May (2017)

F. Göttfert, T. Pleiner, J. Heine, V. Westphal, D. Görlich, S. J. Sahl, S. W. Hell, "Strong signal increase in STED fluorescence microscopy by imaging regions of subdiffraction extent", PNAS 1621495114 (2017)

J. M. Perkel, "Superresolution microscopy", Science, (2016)

A. N. Butkevich, G. Y. Mitronova, S. C. Sidenstein, J. L. Klocke, D. Kamin, D. N. H. Meineke, E. D'Este, P.-T. Kraemer, J. G. Danzl, V. N. Belov, S. W. Hell, "Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super-Resolution STED Microscopy in Living Cells", Angew. Chem. Int. Ed., Feb. (2016)

J. Hanne, F. Goettfert, J. Schimer, M. Anders-Oesswein, J. Konvalinka, J. Engelhardt, B. Mueller, S. W. Hell, H.-G. Kraeusslich "Stimulated Emission Depletion Nanoscopy Reveals Time-Course of Human Immunodeficiency Virus Proteolytic Maturation",  ACS Nano (2016)

O. Steshenko, D. M. Andrade, A. Honigmann, V. Mueller, F. Schneider, E. Sezgin, S. W. Hell, M. Simons, C. Eggeling, "Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy", Biophysical Journal 110, 2441–2450, Jun. (2016)

S. Schnorrenberg, T. Grotjohann, G. Vorbrüggen, A. Herzig, S. W. Hell, S. Jakobs, "In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster", eLife (2016)

L. Große, C. A. Wurm, C. Brüser, D. Neumann, D. C. Jans, S. Jakobs, "Bax assembles into large ring-like structures remodeling the mitochondrial outer membrane in apoptosis", EMBO J., Jan. (2016)

I. Testa, E. D'Este, N. T. Urban, F. Balzarotti, S. W. Hell, "Dual Channel RESOLFT Nanoscopy by Using Fluorescent State Kinetics", Nano Lett. 15(1), 103-106 (2015)

M. Ratz, I. Testa, S. W. Hell, S. Jakobs, "CRISPR/Cas9-mediated endogenous protein tagging for RESOLFT super-resolution microscopy of living human cells", Scientific Reports 5, doi:10.1038/srep09592 (2015)

S. W. Hell, "Nanoscopy with Focused Light (Nobel Lecture)", Angewandte Chemie, Juni 2015 (2015)

S. W. Hell, S. J. Sahl, M. Bates, X. Zhuang, R. Heintzmann, M. J. Booth, J. Bewersdorf, G. Shtengel, H. Hess, P. Tinnefeld, "The 2015 super-resolution microscopy roadmap", Journal of Physics D: Applied Physics, (2015)

G. Y. Mitronova, S. Polyakova, C. A. Wurm, K. Kolmakov, T. Wolfram, D. N. H. Meineke, V. N. Belov, M. John, S. W. Hell, "Functionalization of the meso-Phenyl Ring of Rhodamine Dyes Through SnAr with Sulfur Nucleophiles: Synthesis, Biophysical Characterizations, and Comprehensive NMR Analysis", Eur. J. Org. Chem (2015)

K. Kehrein, R. Schilling, B. V. Möller-Hergt, C. A. Wurm, S. Jakobs, T. Lamkemeyer, T. Langer, M. Ott, "Organization of Mitochondrial Gene Expression in Two Distinct Ribosome-Containing Assemblies", Cell Rep., Feb. 12, pii: S2211-1247(15)00025-X (2015)

I. Testa, E. D'Este, N. T. Urban, F. Balzarotti, S. W. Hell, "Dual Channel RESOLFT Nanoscopy by Using Fluorescent State Kinetics", Nano Lett. 15, 103 - 106. (2015)

L. Westin, M. Reuss, M. Lindskog, A. Aperia, H. Brismar, "Nanoscopic spine localization of Norbin, an mGluR5 accessory protein", BMC Neuroscience (2014)

M. Reuss, B. Harke, "Sub-25 nm Resolution STED Microscopy", Imaging & Microscopy, Dec. (2014)

F. Görlitz, P. Hoyer, H. J. Falk, L. Kastrup, J. Engelhardt, S. W. Hell, "A STED Microscope Designed for Routine Biomedical Applications", Prog. Electromagn. Res. 147, 57 – 68. (2014)

K. Kolmakov, C. A. Wurm, D. N. H. Meineke, F. Göttfert, V. P. Boyarskiy, V. N. Belov, S. W. Hell, "Polar Red-Emitting Rhodamine Dyes with Reactive Groups: Synthesis, Photophysical Properties, and Two-Color STED Nanoscopy Applications", Chem. Eur. J. 20, 146 - 157 (2014)

F. Lavoie-Cardinal, N. A. Jensen, V. Westphal, A. C. Stiel, A. Chmyrov, J. Bierwagen, I. Testa, S. Jakobs, S. W. Hell, "Two-Color RESOLFT Nanoscopy with Green and Red Fluorescent Photochromic Proteins", ChemPhysChem in early view (2014)

M. P. Clausen, S. Galiani, J. Bernardino de la Serna, M. Fritsche, J. Chojnacki, K. Gehmlich, B. C. Lagerholm, C. Eggeling,"Pathways to optical STED microscopy", Nanobioimaging 1-12, (2013)

F. Göttfert, C. A. Wurm, V. Mueller, S. Berning, V. C. Cordes, A. Honigmann, S. W. Hell, "Coaligned Dual-Channel STED Nanoscopy and Molecular Diffusion Analysis at 20 nm Resolution", Biophysical Journal Volume 105, L01–L03 (2013)

A. Chmyrov, J. Keller, T. Grotjohann, M. Ratz, E. d'Este, S. Jakobs, C. Eggeling, S. W. Hell, "Nanoscopy with more than 100,000 'doughnuts'", Nature Meth. 10, 737-740 (2013)

J. V. Chacko, C. Canale, B. Harke, A. Diaspro, "Sub-diffraction nano manipulation using STED AFM", PLoS One. 2013 Jun 17;8(6):e66608

T. Grotjohann, I. Testa, M. Reuss, T. Brakemann, C. Eggeling, S. W. Hell, S. Jakobs, "rsEGFP2 enables fast RESOLFT nanoscopy of living cells", eLIFE (2012)

I. Testa, N. T. Urban, S. Jakobs, C. Eggeling, K. I. Willig, S. W. Hell, "Nanoscopy of Living Brain Slices with Low Light Levels", Neuron 75, 992  (2012)

T. J. Gould, J. Bewersdorf, "Nanoscopy at low light intensities shows its potential", eLIFE (2012)

C. A. Wurm, K. Kolmakov, F. Göttfert, H. Ta, M. Bossi, H. Schill, S. Berning, S. Jakobs, G. Donnert, V. N. Belov, S. W. Hell, "Novel red fluorophores with superior performance in STED microscopy", Optical Nanoscopy 1, 1 – 7 (2012)

M. D. Lesoine, S. Bose, J. W. Petrich, E. A. Smith, "Supercontinuum stimulated emission depletion fluorescence lifetime imaging", J Phys Chem B. Jul 12;116(27):7821-6. doi: 10.1021/jp303912p. Epub 2012 Jun 27. (2012)

S. Berning, K. I. Willig, H. Steffens, P. Dibaj, S. W. Hell, "Nanoscopy in a Living Mouse Brain", Science 335, 551 (2012)

K. Kolmakov, C. A. Wurm, R. Hennig, E. Rapp, S. Jakobs, V. N. Belov, S. W. Hell, "Red-Emitting Rhodamines with Hydroxylated, Sulfonated, and Phosphorylated Dye Residues and Their Use in Fluorescence Nanoscopy" Chemistry", A European Journal 18, 12986 - 12998 (2012)

B. Harke, J. V. Chacko, H. Haschke, C. Canale, A. Diaspro, " A novel nanoscopic tool by combining AFM with STED microscopy", Optical Nanoscopy 2012, 1:3

T. Grotjohann, I. Testa, M. Leutenegger, H. Bock, N. T. Urban, F. Lavoie-Cardinal, K. I. Willig, C. Eggeling, S. Jakobs, S. W. Hell, "Diffraction-unlimited all-optical imaging and writing with a photochromic GFP", Nature 478, 204-208 (2011)

T. Staudt, A. Engler, E. Rittweger, B. Harke, J. Engelhardt, S. W. Hell, "Far-field optical nanoscopy with reduced number of state transition cycles", Opt. Express 19, 5644 – 5657 (2011).

B. R. Rankin, G. Moneron, C. A. Wurm, J. C. Nelson, A. Walter, D. Schwarzer, J. Schroeder, D. A. Colo´n-Ramos, S. W. Hell, "Nanoscopy in a Living Multicellular Organism Expressing GFP", Biophysical J. Volume 100, L63–L65 (2011)

J. Bückers, D. Wildanger, G. Vicidomini, L. Kastrup, S.W. Hell, "Simultaneous multi-lifetime multi-color STED imaging for colocalization analyses", Opt Express Feb 14;19(4):3130-43. doi: 10.1364/OE.19.003130. (2011)

T. Brakemann, A. C. Stiel, G. Weber, M. Andresen, I. Testa, T. Grotjohann, M. Leutenegger, U. Plessmann, H. Urlaub, C. Eggeling, M. C. Wahl, S. W. Hell, S. Jakobs, "A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching", Nature Biotechnol. 29, 942-947 (2011)

G. Vicidomini, G. Moneron, K. Y. Han, V. Westphal, H. Ta, M. Reuss, J. Engelhardt, C. Eggeling, S. W. Hell, "Sharper low-power STED nanoscopy by time gating", Nature Meth. 8, 571 - 573. (2011)

P. Bingen, M. Reuss, J. Engelhardt, S. W. Hell, "Parallelized STED fluorescence nanoscopy", Opt. Express 19, 23716-23726 (2011)

J. Tønnesen, F. Nadrigny, K. I. Willig, R. Wedlich-Söldner, V. Nägerl, "Two-Color STED Microscopy of Living Synapses Using A Single Laser-Beam Pair", Biophys J., 101(10): 2545–2552 (2011)

D. Wildanger, R. Medda, L. Kastrup, S. W. Hell, "A compact STED microscope providing 3D nanoscale resolution", J. Microsc. 236, 35 (2009)

B. Harke, C. K. Ullal, J. Keller, S. W. Hell, "Three-Dimensional Nanoscopy of Colloidal Crystals", Nano Lett. 8, 1309 (2008)

B. Harke, J. Keller, C. K. Ullal, V. Westphal, A. Schönle, S. W. Hell, "Resolution scaling in STED microscopy", Opt. Express 16, 4154-4162 (2008)

E. Auksorius, B. R. Boruah, C. Dunsby, P. M. Lanigan, G. Kennedy, M. A. Neil, P. M. French, "Stimulated emission depletion microscopy with a supercontinuum source and fluorescence lifetimeimaging", Opt Lett., Jan 15;33(2):113-5. (2008)

S. W. Hell, "Far-Field Optical Nanoscopy" Science 316, 1153-1158 (2007)

K. I. Willig, S. O. Rizzoli, V. Westphal, R. Jahn, S. W. Hell, "STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis", Nature, Vol. 440|13 (2006)

G. Donnert, J. Keller, R. Medda, M. A. Andrei, S. O. Rizzoli, R. Lührmann, R. Jahn, C. Eggeling, S. W. Hell, "Macromolecular-scale resolution in biological fluorescence microscopy", PNAS 103, 11440-11445 (2006)